Functional intronic variant of SLC5A10 affects DRG2 expression and survival outcomes of early-stage non-small-cell lung cancer.

Cancer Sci · 2018 · PMC6272084 · PMID 30281872

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an increasing trendno p-value reported

Relative DRG2 mRNA expression showed an increasing trend with the number of rs2257609 C>T polymorphic alleles in non‐malignant lung tissues ( P trend = 0.03, Figure 2 C). 3.4 Effect of rs2257609 C>T on promoter activity We investigated whether rs2257609 C>T modulated the activity of the DRG2 promoter using a luciferase assay.

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