Improved Production and Antitumor Properties of Triterpene Acids from Submerged Culture of Ganoderma lingzhi.

The linear term x 1 (initial pH) had an extremely significant effect on TA production ( p < 0.01), followed by x 3 (temperature) ( p < 0.05).

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ANOVA of the quadratic regression model revealed that the model was highly significant, as evidenced by the low p value for the Fisher’s F -test (( p model > F ) < 0.0001) ( Table 4 ).

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