STAT3 siRNA resulted in a highly significant and CELLULAR & MOLECULAR BIOLOGY LETTERS 347 reproducible reduction of STAT3 expression ranging from 70 to 95% in a concentration dependent manner at 24 h (Fig. 2).
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STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL.
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