Furthermore, multivariate analysis revealed that the differences was significant between groups I and III in OS, and also had a tendency toward statistical significance in TTR (training cohort, OS, P < 0.0001 and TTR, P = 0.069; validation cohort, OS, P = 0.001 and TTR, P = 0.001) ( Table S5 ).
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Clinical significance of PD-1/PD-Ls gene amplification and overexpression in patients with hepatocellular carcinoma.
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0.0001
0.0001