Barely Significant
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Phototransduction and circadian entrainment are the key pathways in the signaling mechanism for the baculovirus induced tree-top disease in the lepidopteran larvae.

Sci Rep · 2018 · PMC6277413 · PMID 30510155

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hedged sentence
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The sentences

highly significantP < 0.0001actually significant
However, highly significant ( P < 0.0001) effect of both zeitgeber time and zeitgeber time × experimental groups interaction was observed on per gene expression.

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