CD4 + cell counts less than 500 or CD4 + : CD8 + ratios less than 0.5 at 1 year prior to endpoint were significant only in adjusted models, whereas nadir values were marginally significant (Supplemental Digital Contents 2 and 3 and Table 2 ).
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Increased risk of anal squamous cell carcinoma in HIV-positive men with prior hepatitis B virus infection.
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