Adenosine A₁ Receptor mRNA Expression by Neurons and Glia in the Auditory Forebrain.

Is presynaptic A 1 R‐adenosine signaling also involved in regulating glutamate release in all of these projections? It may be significant that while plasticity becomes gated at mature TC synapses, cortico‐cortical synapses remain plastic after critical periods close (Amitai, 2001 ; Froemke et al., 2007 ; Jiang et al., 2007 ; Oswald and Reyes, 2008 , 2011 ; Huang et al., 2012 ), suggesting different regulatory mechanisms for TC and CC projections.

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