Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis.

However, the hepatic fibrosis/HSC activation pathway was highly significant for the TGF-β data set (-log[ P value], 5.6), whereas treatment with PDGF-BB was not as dominant as TGF-β for this domain (-log[ P value], 2.686) ( Figure 1 D ).

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