An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma.

Nat Commun · 2018 · PMC6283830 · PMID 30523261

Europe PMC DOI

hedged sentence

0.0555

closest p · 1.1× alpha

0.0555

boldest claim

The sentences

borderline significantp = 0.0555so close (0.05 < p ≤ 0.1)

Administration of anti-Ly6G antibody significantly suppressed CCRK-induced PMN-MDSC accumulation in liver ( p < 0.01), leading to a borderline significant reduction in HCC tumorigenicity ( p = 0.0555; Supplementary Fig. 5e, f ).

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