Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors.

Nat Commun · 2018 · PMC6286392 · PMID 30531873

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highly significantno p-value reported

The miRNA identified as positively and negatively associated with the hallmarks gene signatures in this dataset showed highly significant concordance, over the majority of signatures, with the results obtained in analysis of the TCGA BRCA dataset (Supplementary Figure 12 , Supplementary Note 5a ).

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