Pharmacokinetic Interactions of Clinical Interest Between Direct Oral Anticoagulants and Antiepileptic Drugs.

Front Neurol · 2018 · PMC6292857 · PMID 30581412

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might be significantno p-value reported

In conclusion, the risk of drug-drug interaction might be significant among patients taking AEDs and DOACs simultaneously, at least for some AEDs; future studies will help to better quantify this risk and to facilitate an optimal therapeutic handling of these patients.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.