Prognostic value of procalcitonin and lipopolysaccharide binding protein in cancer patients with chemotherapy-associated febrile neutropenia presenting to an emergency department.

Regarding to the performance of MASCC score and biomarker levels as predictor tools ( Figure 2 ), MASCC score and PCT concentrations, measured at presentation to the ED, showed a similar and good ability to predict the development of serious complications, with ROC AUCs of 0.83 (95% confidence interval (CI): 0.74 - 0.89) and 0.85 (95% CI: 0.77 - 0.91), respectively, both higher than LBP (ROC AUC: 0.70 (95% CI: 0.61 - 0.78), although the difference was marginally significant (P = 0.054) when ROC AUCs of MASCC score and LBP were compared ( Table 3 ).

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