Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM.

Cell Death Dis · 2018 · PMC6294248 · PMID 30546006

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highly significantno p-value reported

The combination produced a highly significant reduction in intracranial growth of U87 cells whereas ADI-PEG20 monotherapy had only a minor effect.

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