Optimising the antibiotic treatment of uncomplicated acute appendicitis: a protocol for a multicentre randomised clinical trial (APPAC II trial).

BMC Surg · 2018 · PMC6296129 · PMID 30558607

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an increasing trendno p-value reported

The lifetime risk of acute appendicitis in males is 8.6 and 6.7% in females [ 1 ] with recent meta-analysis showing an increasing trend in the incidence of appendicitis in the newly industrialised countries [ 2 ].

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