borderline significanceP = 0.05
As a result, hENT1 was found to be associated only with PFS, in agreement with other studies on BTC [ 12 – 14 ], and borderline significance of the difference in PFS (24 and 11 weeks, P = 0.05) was observed between the high- and low-hENT1 groups, although there was no significant difference in overall survival (52 and 26 weeks, P = 0.15).