Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients.

Further none of the secondary variables did show any significant differences from placebo apart from MMTT AUC C-peptide 0-4h and GGI AUC Glucose0-1h which showed mechanistically contradictory borderline significant effects of p = 0.04 and 0.045 respectively (Fig F in S1 File and Table 2 ).

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