After post hoc comparisons, we found an increasing trend of mALFF/mfALFF values in the Hippocampus_L (aal), Frontal_Mid_Orb_R (aal), Frontal_Sup_R (aal) and Paracentral_Lobule_R (aal) as disease progressed (Figure 4 ).
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Gradual Disturbances of the Amplitude of Low-Frequency Fluctuations (ALFF) and Fractional ALFF in Alzheimer Spectrum.
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Several brain regions presented a decreasing trend of mALFF/mfALFF values in the four groups, including the Cingulum_Mid_R (aal), bilateral inferior Cerebellum lobe, bilateral precuneus and the Cingulum_Ant_R (aal) as disease progressed (Figure 3 ).