highly significantP <.001
Analysis by Program Type The mixed-effects linear model for depression as measured by the PHQ-9 ( Figure 1 ) showed highly significant changes in scores over time for those who chose the Space from Depression program ( F 2,6 =13.7, P <.001), with decreases from baseline to 8-week (mean difference 5.0, 95% CI 3.0-7.1) and 3-month (mean difference 4.3, 95% CI 2.1-6.4) follow-up.