Therefore, also in brain metastatic NSCLC patients, the detected EpCAM-positive CTCs could indicate CSCs properties, and would thus explain the highly significant association of even one CTC/7.5 ml with a poor patient outcome.
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Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease.
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