The Effect of a High-Dose Vitamin B Multivitamin Supplement on the Relationship between Brain Metabolism and Blood Biomarkers of Oxidative Stress: A Randomized Control Trial.

In contrast, at 6 months post-treatment there were significant, positive correlations between vitamin B6 levels and NAA (ρ = 0.523, p = 0.007), creatine (ρ = 0.413, p = 0.040), and choline (ρ = 0.489, p = 0.013) concentrations; and vitamin B12 and creatine concentrations (ρ = 0.406, p = 0.041), whereas there was marginal significance for choline concentration (ρ = 0.359, p = 0.073).

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