Systems Analysis of Transcriptomic and Proteomic Profiles Identifies Novel Regulation of Fibrotic Programs by miRNAs in Pulmonary Fibrosis Fibroblasts.

Genes (Basel) · 2018 · PMC6316743 · PMID 30501089

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highly significantno p-value reported

Their identification as important miRNAs modulating distinct aspects of the fibrotic transcriptomes in IPF and SSc lung fibroblasts is highly significant in our view, as this further supports a role for miR-29 as a master ECM regulator, and reveals novel roles for miR-138-5p and miR-146b-5p in pulmonary fibrosis.

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