Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls.

In line with the elevated S-ASM activities in patients, we have found strong and highly significant correlations of S-ASM with these liver enzyme activities (Rho > 0.37 and p < 6 × 10 −8 for all three enzymes, Table 2 , Figure 3 ).

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