An Evaluation of the Potential of NMR Spectroscopy and Computational Modelling Methods to Inform Biopharmaceutical Formulations.

Pharmaceutics · 2018 · PMC6320905 · PMID 30248922

Europe PMC DOI

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highly significantno p-value reported

This structural and kinetic study of the protofibril formation was highly significant as the build-up of toxic, soluble aggregate forms of Aβ, then forms larger assemblies which contribute to the development of Alzheimer’s disease.

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