This highly significant finding is supported by our previous work, which demonstrates that P-gp colocalizes with caveolar proteins (i.e., caveolin-1, cavin-1, and cavin-2) in membrane fractions derived from intact brain microvessels [ 123 ].
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Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity.
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