Fully automated sequence alignment methods are comparable to, and much faster than, traditional methods in large data sets: an example with hepatitis B virus.

PeerJ · 2019 · PMC6321758 · PMID 30627489

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may be significantno p-value reported

These differences may be significant in data sets where manual editing is especially challenging: for example, data sets with many sequences (>10,000) and varying sequence lengths.

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