We found little evidence for HRs differing across type of initial presentation ( P for interaction = 0.87), but a statistical trend towards an interaction between treatment and FFR ( P for interaction = 0.06), with a particularly pronounced benefit of FFR-guided PCI in patients who had at least one lesion with an FFR of 0.80 or less (HR 0.62, 95% CI 0.43–0.89; P = 0.01).
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Fractional flow reserve-guided percutaneous coronary intervention vs. medical therapy for patients with stable coronary lesions: meta-analysis of individual patient data.
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