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Infliximab use in ulcerative colitis flare with clostridium difficile infection: A report of two cases and literature review.

North Clin Istanb · 2018 · PMC6323562 · PMID 30688931

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an increasing trendno p-value reported
The incidence and severity of CDI in IBD has shown an increasing trend in the last two decades.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.