Association of Impaired Cytochrome P450 2D6 Activity Genotype and Phenotype With Therapeutic Efficacy of Primaquine Treatment for Latent Plasmodium vivax Malaria.

JAMA Netw Open · 2018 · PMC6324265 · PMID 30646129

Europe PMC DOI

hedged sentence

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantP < .001actually significant

An analysis of correlation between genotype-determined activity score and log metabolic ratio of urinary dextromethorphan to dextrorphan proved to be highly significant (Spearman correlation coefficient = −0.683; P < .001) (eAppendix and eFigure 4 in the Supplement ).

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