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Antimicrobial resistance of <i>Vibrio cholerae</i> from sub-Saharan Africa: A systematic review.

Afr J Lab Med · 2018 · PMC6325272 · PMID 30643734

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an increasing trendno p-value reported
40 An increasing trend of resistance to cotrimoxazole was observed from many studies.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.