PC has shown an increasing trend, and the 5-year survival rate is only 8% as one of the leading causes of cancer death [ 1 – 3 ], mainly due to its late presentation, low surgical resectability rate, limited treatment, resistance to standard radiotherapy and chemotherapy, and recurrence [ 4 ].
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RER1 enhances carcinogenesis and stemness of pancreatic cancer under hypoxic environment.
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