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miRNA-373 promotes urinary bladder cancer cell proliferation, migration and invasion through upregulating epidermal growth factor receptor.

Exp Ther Med · 2019 · PMC6327664 · PMID 30679992

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an increasing trendno p-value reported
With the growth of the aging population and changes in exposure to risk factors, the incidence of urinary bladder cancer demonstrates an increasing trend and the age of onset is decreasing ( 1 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.