Invasive pneumococcal diseases in children and adults before and after introduction of the 10-valent pneumococcal conjugate vaccine into the Austrian national immunization program.

The 2–4 years old already showed a decreasing trend in PCV10 (VT)-IPD during the pre-period, which along with slowly increasing PCV10 coverage among the <5 years old during the post-period explain the lower vaccine effectiveness among the <5 years old, compared to other observations.

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