Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn.

Pain · 2019 · PMC6330098 · PMID 30247267

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highly significantP < 0.0001actually significant

Substance P cells showed a higher frequency of both sEPSCs and mEPSCs (6.04 ± 0.96 Hz sEPSCs, 3.24 ± 0.67 Hz mEPSCs, n = 27 and 11, respectively) than GRP cells (0.2 ± 0.05 Hz sEPSCs, 0.02 ± 0.01 Hz mEPSCs, n = 120 and 32, respectively), and these differences were both highly significant (sEPSC, Mann–Whitney, U = 68, P < 0.0001; mEPSC, Mann–Whitney, U = 0, P < 0.0001; Fig. 6 ).

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