Main effect of patients vs healthy controls A direct group comparison across all conditions (BD > HC, p = 0.05 FWE corrected) revealed highly significant increases in the patients for medial brain areas including sgACC (T = 8.08, x = 3, y = 29, z = − 11), vmPFC (T = 9.95, x = − 6, y = 41, z = − 23, T = 8.25, x = − 12, y = 41, z = − 8), and PCC (T = 6.95, x = − 6, y = − 34, z = 46), as well as in the inferior parietal cortex (L: T = 9.10, x = − 45, y = − 61, z = 37, R: T = 8.96, x = 60, y = − 55, z = 28), and superior occipital gyrus (R: T = 13.59, x = 24, y = − 88, z = 34), as shown in Fig. 2 a (in red).
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Rumination related activity in brain networks mediating attentional switching in euthymic bipolar patients.
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