Cosmeceutical activities of ethanol extract and its ethyl acetate fraction from coffee silverskin.

However, a decreasing trend in MMP-1 release was observed as the concentration of the EtOAc fraction of coffee silverskin increased, and a significant decrease of 74.27% was observed compared to that in the UVB-treated control when the cells were pretreated with 25 μg/mL EtOAc fraction (Fig. 5 b).

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In recent years, there has been an increasing trend of developing multifunctional cosmetics with benefits such as anti-aging, whitening, moisturizing, and ultraviolet (UV) radiation-protective efficacy.

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