For other markers of brite cell abundance (cell death-inducing DNA fragmentation factor alpha-like effector A, cytochrome C oxidase subunit 7a2, otopetrin 1), cholate supplementation rather alleviated high fat diet-induced reduction, a trend that failed to reach significance.
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Bile acid supplementation decreases body mass gain in C57BL/6J but not 129S6/SvEvTac mice without increasing energy expenditure.
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