In that line, enhanced IgG level against latent protein EBNA-1 in MS patients was significantly associated with risk alleles of single nucleotide polymorphism within SOX8, MYB, CARD11, as well as a trend toward significance for HLA-DRB1 * 1501 (Kreft et al., 2017).
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The role of Epstein-Barr virus in multiple sclerosis: from molecular pathophysiology to <i>in vivo</i> imaging.
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