Updates in Clinical and Genetics Aspects of Hypermobile Ehlers Danlos Syndrome

Balkan Med J · 2019 · PMC6335943 · PMID 30063214

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highly significantno p-value reported

A 2004 twin study on 483 monozygotic and 472 dizygotic female twin pairs, conducted in the UK, reported an estimated heritability of 70% and a higher concordance for JH in the monozygotic twins (60%) than in the dizygotic twins (36%), suggesting that JH has a highly significant genetic component ( 27 ).

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