Barely Significant
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Identifying optimal candidates for local treatment of the primary tumor among patients with de novo metastatic nasopharyngeal carcinoma: a retrospective cohort study based on Epstein-Barr virus DNA level and tumor response to palliative chemotherapy.

BMC Cancer · 2019 · PMC6341516 · PMID 30665378

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a decreasing trendno p-value reported
Besides, gross tumor volume showed a decreasing trend during treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.