Barely Significant
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Topical treatment of vaginal dryness with a non-hormonal cream in women undergoing breast cancer treatment - An open prospective multicenter study.

PLoS One · 2019 · PMC6345451 · PMID 30677065

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highly significantno p-value reported
Moreover, application of the product resulted in a highly significant reduction regarding severity of objective findings of vaginal dryness, such as thinning of the vaginal epithelium, redness and petechial bleedings, and at day 28, all patients were free of petechial bleedings.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.