Antagonistic paralogs control a switch between growth and pathogen resistance in C. elegans.

Interestingly, nearly all of the IPR genes described above are also induced following bortezomib treatment ( Fig 6E ), an overlap that is highly significant (representation factor (rf) = 10.8; p<2.68E-74; rf is the ratio of actual overlap to expected overlap where rf>1 indicates overrepresentation and rf<1 indicates underrepresentation; see Materials and Methods ).

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