Multiscale Agent-Based and Hybrid Modeling of the Tumor Immune Microenvironment.

We break the review into the following sections, although there may be significant overlap: (1) Models focusing on immune-related tumor mechanobiology (2) Models focusing on tumor-associated vasculature in the immune response (3) Models focusing on tumor-associated lymphatics and lymph nodes (4) Models focusing on tumor immunotherapy (5) Models focusing on tumor-enhancing immune cells (6) Models focusing on intra-tumor heterogeneity 3.1.

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