The metabolic alterations within the normal appearing brain in patients with Hashimoto's thyroiditis are correlated with hormonal changes.

There was a statistically significant decrease of the NAA/Cr ratios in HT patients in groups with different disease length in comparison to the healthy controls, except from the group 1 (duration of the disease 2–5 years) in the PWM region, however the p value was close to the margin of statistical significance ( p = 0.05).

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