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The evolving epidemiology of rotavirus A infection in Brazil a decade after the introduction of universal vaccination with Rotarix®.

BMC Pediatr · 2019 · PMC6354375 · PMID 30704518

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an increasing trendno p-value reported
Interestingly, after RV1 introduction, RVA-positivity showed an increasing trend in children aged 25–48 months-old.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.