Integrin-linked kinase (ILK) and src homology 2 domain-containing phosphatase 2 (SHP2): Novel targets in EGFR-mutation positive non-small cell lung cancer (NSCLC).

In the multivariate Cox regression model, ILK mRNA expression remained highly significant for progression-free survival with a HR of 3.74 (95% CI 1.33 to 10.56), ( P = .0126) ( Table 1 ). 3.3 Overall survival The effect of the five biomarkers on the survival of the 64 EGFR-mutation positive NSCLC patients included in our study, was also examined.

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