Barely Significant
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R-loop formation during S phase is restricted by PrimPol-mediated repriming.

EMBO J · 2019 · PMC6356060 · PMID 30478192

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highly significantno p-value reported
In contrast, primpol cells exhibit a highly significant increase in R‐loop signal around the repeat.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.