Predicting and understanding the response to short-term intensive insulin therapy in people with early type 2 diabetes.

Consequently, this relatively large number of overtargeted genes was also highly significant ( P = 0.0039, as empirically determined by comparison to 10000 simulated equivalent random networks).

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Interestingly, the changes in let-7a-5p, miR-195-5p, miR-320b, and miR-138-5p appear coregulated to some extent, as suggested by significant (|r| > 0.4, P < 0.05) and marginally significant (|r| > 0.4, P ≤ 0.062) correlations among them ( Figure 3 G–I).

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