miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition.

Transfection of DU145 and PC-3 cell lines – which inherently express almost undetectable levels of the miRNA [ 17 ] – with a miR-205 synthetic mimic resulted in its persistent endogenous expression, still appreciable after ten days, being the values of relative expression highly significant, albeit reduced over time.

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