An interesting trend was also observed in both RA patient groups, where the percentage of NK cells within the SFs seemed to correlate with disease activity (DAS28CRP).
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High percentages and activity of synovial fluid NK cells present in patients with advanced stage active Rheumatoid Arthritis.
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Blood NK cells are made up of around 10% CD56 bright and 90% CD56 dim NK cells, whereas the NK cells in the SFs of DRA and NDRA patients had a highly significant expansion of the CD56 bright phenotype (37.7 ± 7.9 in NDRA and 39.9% ± 10.4 in DRA, Fig. 1 ).