We identified 560 differentially variable and differentially methylated CpGs (DVMCs) associated to CD in the epithelial cell population, out of which 93.6% were more variable in the disease group, and were borderline significant for the IBD pathway (FDR = 0.05798).
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The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region.
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